Tip-off is set for 4 p.m. at the Pete Maravich Assembly Center. ESPNU will televise the tilt, with Tom Hart providing play-by-play analysis and Matt Doherty serving as the color commentator.
Both squads currently sit below .500 in SEC play. The Bulldogs (7-16, 2-9) fell 78-36 to Missouri on Wednesday, while the Tigers (14-8, 5-6) got back into the win column with 64-46 win at South Carolina on Thursday.
The last two games in the series have been decided by Anthony Hickey field goals in the final seconds. Hickey hit a pull-up jumper with 1.4 seconds remaining to give LSU the 69-68 comeback victory two weeks ago. He also made a floater with 1.5 seconds left in last year's matchup in Baton Rouge to give the Tigers an overtime win.
Mississippi State has not lost back-to-back games in Baton Rouge since 2005-2006 and has won five of the last eight meetings overall against the Bayou Bengals.
Fred Thomas paces the Bulldogs in scoring with 10.2 points per outing. Trivante Bloodman leads Coach Rick Ray's squad in assists with 2.7 a game, and against Missouri he scored a career-high 13 points.
Turnovers could play a huge factor in Saturday's game. MSU has the lowest assist-to-turnover ratio in the Southeastern Conference, while LSU leads the league in steals thanks to Hickey's nation's best 3.4 takeaways per outing.
Following Saturday's contest, the Bulldogs wrap up their two-game road trip at Alabama on Wednesday. The SEC Network will televise the 7 p.m. clash in Tuscaloosa.