CSS will handle the broadcast, with Matt Stewart handling play-by-pay duties and Kyle Macy serving as the analyst.
Dating back to last year, the Bulldogs (7-7, 2-0) have won four-straight SEC games.
"Obviously, I'm really pleased with our start in SEC play," MSU coach Rick Ray said. "I thought we had really turned a corner as a ball club with the win against New Orleans, and then to go out and win a game against South Carolina, then especially going on the road and winning at Georgia, I think our team is steadily improving. Depth obviously is obviously still a concern and a problem."
After holding off South Carolina 56-54 a week ago, Mississippi State rallied from a 7-point deficit to upend Georgia, 72-61.
Junior guard Jalen Steele keyed the win with a career-high 21-point effort. He was joined in double-digit scoring by Craig Sword, who totaled 16 points en route to garnering SEC Freshman of the Week honors.
MSU, which has won 12 of the last 15 outings against the Crimson Tide at Humphrey Coliseum, is led in scoring by sophomore forward Roquez Johnson at 12.0, while Gavin Ware is tops on the boards at 7.1.
Last year in Starkville, the Bulldogs claimed a 56-52 win against Bama.
This season, the Tide rolls into town sporting a 9-6 overall ledger and 1-1 conference mark following its 68-65 win against Tennessee on Saturday. In its league opener, Alabama lost at Missouri, 84-68.
The Crimson Tide is led in scoring by guard Trevor Releford at 16.3 points a game, while Trevor Lacey is second at 12.5 points, followed by Rodney Cooper at 11.7.
After Wednesday, MSU is on the road for two games, starting with a trip to Tennessee on Saturday before traveling to Arkansas Wednesday.